The total number record retrieved from this search are 9. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_3138	Herpes simplex virus	HSV-HSV-GR	DNA	Herpesviridae	Deletion of gamma 34.5 gene and insertion of GR and mcherry	Yes	No	No	National cell bak of Iran	Murine breast cancer cell line	4T1	NA	NA	Photomicrography and flow cytometry	1 MOI	27.9% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	30936930
OV_3139	Herpes simplex virus	HSV-HSV-GR	DNA	Herpesviridae	Deletion of gamma 34.5 gene and insertion of GR and mcherry	Yes	No	No	National cell bak of Iran	Murine breast cancer cell line	TC-1	NA	NA	Photomicrography and flow cytometry	1 MOI	21.2% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	30936930
OV_3140	Herpes simplex virus	HSV-HSV-GR	DNA	Herpesviridae	Deletion of gamma 34.5 gene and insertion of GR and mcherry	Yes	No	No	National cell bak of Iran	Murine breast cancer cell line	CT-26	NA	NA	Photomicrography and flow cytometry	1 MOI	21.3% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	30936930
OV_4416	Adenovirus	ONYX-015	DNA	Adenoviridae	None	No	Virus in combination with melphalan (2.5 microgram)	No	St. Joseph healthcare, London	Human head and neck squamous cell carcinoma	HN-5a	NA	NA	Flow cytometry	20 pfu	3% cancer cell death after day 3	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4417	Adenovirus	ONYX-015	DNA	Adenoviridae	None	No	Virus in combination with melphalan (5 microgram)	No	St. Joseph healthcare, London	Human head and neck squamous cell carcinoma	HN-5a	NA	NA	Flow cytometry	20 pfu	6% cancer cell death after day 3	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4418	Adenovirus	ONYX-015	DNA	Adenoviridae	None	No	Virus in combination with melphalan (7.5 microgram)	No	St. Joseph healthcare, London	Human head and neck squamous cell carcinoma	HN-5a	NA	NA	Flow cytometry	20 pfu	10% cancer cell death after day 3	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4419	Adenovirus	ONYX-015	DNA	Adenoviridae	None	No	Virus in combination with melphalan (2.5 microgram)	No	St. Joseph healthcare, London	Human head and neck squamous cell carcinoma	HN-5a	NA	NA	Flow cytometry	20 pfu	3% cancer cell death after day 3	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4420	Adenovirus	ONYX-015	DNA	Adenoviridae	None	No	Virus in combination with melphalan (5 microgram)	No	St. Joseph healthcare, London	Human head and neck squamous cell carcinoma	HN-5a	NA	NA	Flow cytometry	20 pfu	15% cancer cell death after day 3	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4421	Adenovirus	ONYX-015	DNA	Adenoviridae	None	No	Virus in combination with melphalan (7.5 microgram)	No	St. Joseph healthcare, London	Human head and neck squamous cell carcinoma	HN-5a	NA	NA	Flow cytometry	20 pfu	25% cancer cell death after day 3	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639